{"id":14255,"date":"2026-10-31T21:18:30","date_gmt":"2026-10-31T21:18:30","guid":{"rendered":"https:\/\/cehpi.com\/?p=14255"},"modified":"2026-10-31T22:07:09","modified_gmt":"2026-10-31T22:07:09","slug":"pharmacoepidemiologie-en-afrique-des-donnees-a-la-decision","status":"publish","type":"post","link":"https:\/\/cehpi.com\/en\/pharmacoepidemiologie-en-afrique-des-donnees-a-la-decision\/","title":{"rendered":"Pharmaco\u00e9pid\u00e9miologie en Afrique : des donn\u00e9es \u00e0 la d\u00e9cision"},"content":{"rendered":"<style>.cehpi-pe{max-width:760px;margin:0 auto;padding:0 20px;color:#2E2A3B;box-sizing:border-box}.cehpi-pe *{box-sizing:border-box}.cehpi-pe p,.cehpi-pe li{font-size:18px!important;line-height:1.72!important;color:#2E2A3B!important;margin:0 0 1.05em!important}.cehpi-pe strong{color:#1F1A2E;font-weight:700}.cehpi-pe h2{font-size:25px!important;line-height:1.3!important;color:#5B2E96!important;font-weight:700!important;margin:2.1em 0 .75em!important;padding:0 0 0 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span{display:block;font-size:14px;line-height:1.4;color:#4A4260}.cehpi-pe .pe-step i{display:inline-block;width:24px;height:24px;border-radius:50%;background:#7ACC44;color:#fff;font-style:normal;font-weight:700;font-size:13px;line-height:24px;text-align:center;margin-bottom:8px}.cehpi-pe .pe-step.last{background:#5B2E96;border-color:#5B2E96}.cehpi-pe .pe-step.last b,.cehpi-pe .pe-step.last span{color:#fff}.cehpi-pe .pe-concl{background:#F2F9EC;border-left:5px solid #7ACC44;border-radius:0 16px 16px 0;padding:26px 28px 10px;margin:8px 0 34px}@media (max-width:700px){.cehpi-pe .pe-pres{grid-template-columns:1fr}.cehpi-pe .pe-lead{font-size:19px!important}.cehpi-pe{padding:0 16px}.cehpi-pe p,.cehpi-pe li{font-size:17px!important}.cehpi-pe h2{font-size:22px!important}.cehpi-pe .pe-stats{grid-template-columns:repeat(2,1fr)}.cehpi-pe .pe-chain{grid-template-columns:1fr}.cehpi-pe .pe-concl{padding:22px 20px 6px}}<\/style>\n<div class=\"cehpi-pe\" lang=\"fr\">\n<figure class=\"pe-cover\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/cehpi.com\/wp-content\/uploads\/2026\/10\/Affiche_Synthese_Panel_PE_Afrique_1920x1080.png\" alt=\"Pharmaco\u00e9pid\u00e9miologie en Afrique : des donn\u00e9es \u00e0 la d\u00e9cision. Synth\u00e8se du panel scientifique international SeminalSeminars\u00ae, \u00c9dition 2, CEHPI\" width=\"1920\" height=\"1080\" loading=\"eager\"><\/figure>\n<p class=\"pe-lead\">D\u00e9fis, opportunit\u00e9s et perspectives pour les syst\u00e8mes de sant\u00e9 africains<\/p>\n<p class=\"pe-meta\">Panel en ligne du 9 octobre 2026 \u00b7 CEHPI \u00b7 <a href=\"#replay\">\u25b6 Voir le replay<\/a> \u00b7 <a href=\"#presentations\">Pr\u00e9sentations (PDF)<\/a><\/p>\n<p>Le 9 octobre 2026, CEHPI a organis\u00e9 la deuxi\u00e8me \u00e9dition de <strong>SeminalSeminars\u00ae<\/strong>. Cinq experts venus d\u2019Afrique et du Canada y ont d\u00e9battu d\u2019une question centrale : <strong>comment faire de la pharmaco\u00e9pid\u00e9miologie un v\u00e9ritable outil de d\u00e9cision pour les syst\u00e8mes de sant\u00e9 africains ?<\/strong><\/p>\n<p>Les \u00e9changes ont fait ressortir un constat simple. Les syst\u00e8mes de sant\u00e9 africains produisent d\u00e9j\u00e0 de nombreuses donn\u00e9es (dossiers m\u00e9dicaux, prescriptions, dispensations, r\u00e9sultats biologiques, registres, syst\u00e8mes de pharmacovigilance, programmes de sant\u00e9, assurances maladie), et ces volumes vont continuer d\u2019augmenter. Le d\u00e9fi consiste d\u00e9sormais \u00e0 transformer ces donn\u00e9es en <strong>preuves fiables, pertinentes et utilisables pour la d\u00e9cision<\/strong>.<\/p>\n<p class=\"pe-stats-t\">Le panel en chiffres<\/p>\n<div class=\"pe-stats\">\n<div class=\"pe-stat\"><span class=\"pe-num\">345<\/span><span class=\"pe-lab\">inscriptions uniques<\/span><\/div>\n<div class=\"pe-stat\"><span class=\"pe-num\">23+<\/span><span class=\"pe-lab\">pays parmi les inscrits<\/span><\/div>\n<div class=\"pe-stat\"><span class=\"pe-num\">\u2248150<\/span><span class=\"pe-lab\">participants Zoom<\/span><\/div>\n<div class=\"pe-stat\"><span class=\"pe-num\">82 min<\/span><span class=\"pe-lab\">de pr\u00e9sence m\u00e9diane<\/span><\/div>\n<\/div>\n<h2>Une discipline au service de plusieurs niveaux de d\u00e9cision<\/h2>\n<p>La pharmaco\u00e9pid\u00e9miologie \u00e9tudie l\u2019utilisation, l\u2019efficacit\u00e9 et la s\u00e9curit\u00e9 des m\u00e9dicaments et des autres produits de sant\u00e9 dans leurs conditions r\u00e9elles d\u2019utilisation. Elle compl\u00e8te en cela les essais cliniques. Au-del\u00e0 de ce qu\u2019un produit <em>peut<\/em> faire dans des conditions contr\u00f4l\u00e9es, elle renseigne sur ce qu\u2019il <em>fait r\u00e9ellement<\/em> dans les populations et les syst\u00e8mes de soins.<\/p>\n<p>Plusieurs champs d\u2019application concernent tout particuli\u00e8rement les syst\u00e8mes de sant\u00e9 africains. La pharmaco\u00e9pid\u00e9miologie peut aider \u00e0 mesurer l\u2019impact r\u00e9el des programmes de sant\u00e9, \u00e0 documenter l\u2019adh\u00e9sion th\u00e9rapeutique et l\u2019usage des m\u00e9dicaments, \u00e0 quantifier et caract\u00e9riser les risques apr\u00e8s la mise sur le march\u00e9, ou encore \u00e0 alimenter les d\u00e9cisions de remboursement et l\u2019\u00e9valuation des technologies de sant\u00e9. Elle se trouve donc au croisement de d\u00e9cisions <strong>cliniques, programmatiques, r\u00e9glementaires et de couverture sanitaire<\/strong>.<\/p>\n<p>Pour que les donn\u00e9es probantes produites soient r\u00e9ellement utiles, il faudrait toutefois partir moins souvent du jeu de donn\u00e9es disponible, ou de la seule question acad\u00e9mique, et davantage de <strong>la d\u00e9cision \u00e0 prendre<\/strong>. Quelle information pourrait modifier cette d\u00e9cision ? De quelles donn\u00e9es a-t-on besoin ? Dans quels d\u00e9lais l\u2019analyse doit-elle \u00eatre produite ?<\/p>\n<h2>Les donn\u00e9es existent, mais doivent devenir exploitables<\/h2>\n<p>Le panel a insist\u00e9 sur ce point : l\u2019Afrique <strong>ne part pas de z\u00e9ro<\/strong>. Les donn\u00e9es de vie r\u00e9elle sont d\u00e9j\u00e0 g\u00e9n\u00e9r\u00e9es dans les soins, les registres, les cohortes, les programmes et la pharmacovigilance. Elles peuvent d\u00e9crire les pratiques, mettre en \u00e9vidence des in\u00e9galit\u00e9s entre populations ou territoires et \u00e9clairer les d\u00e9cisions de sant\u00e9 publique.<\/p>\n<p>Qu\u2019elles existent ne garantit pas pour autant leur utilit\u00e9 scientifique. Les difficult\u00e9s portent notamment sur la <strong>compl\u00e9tude<\/strong>, la comparabilit\u00e9 des d\u00e9finitions et des pratiques de saisie, la pertinence des variables et la tra\u00e7abilit\u00e9 des donn\u00e9es. En pharmaco\u00e9pid\u00e9miologie, le suivi longitudinal compte aussi beaucoup, car il faut pouvoir relier dans le temps la prescription, la dispensation, les r\u00e9sultats biologiques, les \u00e9v\u00e9nements cliniques et les issues de sant\u00e9. Or la fragmentation des syst\u00e8mes et l\u2019absence d\u2019identifiants fiables rendent souvent cette reconstruction difficile.<\/p>\n<p>Quatre conditions apparaissent d\u00e8s lors essentielles : <strong>qualit\u00e9 et standardisation, longitudinalit\u00e9, interop\u00e9rabilit\u00e9 et gouvernance<\/strong>. Il faut y ajouter la ma\u00eetrise des biais de s\u00e9lection, de classement et de confusion, sans laquelle on risque de confondre association observ\u00e9e et relation causale.<\/p>\n<h2>Construire simultan\u00e9ment les infrastructures et les comp\u00e9tences<\/h2>\n<p>Une pharmaco\u00e9pid\u00e9miologie durable a besoin d\u2019infrastructures de donn\u00e9es, mais aussi de cadres de gouvernance, d\u2019\u00e9thique, de protection des informations personnelles et d\u2019assurance qualit\u00e9. La confiance doit porter \u00e0 la fois sur les donn\u00e9es elles-m\u00eames, sur les chercheurs qui les exploitent, sur les r\u00e9sultats produits et sur l\u2019usage qui est fait des informations de sant\u00e9 des populations.<\/p>\n<p>Le d\u00e9veloppement des comp\u00e9tences doit \u00eatre pens\u00e9 \u00e0 plusieurs niveaux. Il faut des professionnels capables de lire et d\u2019utiliser les r\u00e9sultats, des sp\u00e9cialistes form\u00e9s en pharmaco\u00e9pid\u00e9miologie, en biostatistique et en inf\u00e9rence causale, et des chercheurs capables de concevoir des \u00e9tudes, d\u2019adapter les m\u00e9thodes et de produire des connaissances. Les formations existantes, notamment le Master en Pharmacovigilance et Pharmaco\u00e9pid\u00e9miologie de l\u2019Universit\u00e9 Nazi Boni, offrent une base sur laquelle b\u00e2tir des programmes plus larges et des collaborations internationales.<\/p>\n<p>Du c\u00f4t\u00e9 r\u00e9glementaire, les besoins sont particuli\u00e8rement importants. Surveiller activement les m\u00e9dicaments et les vaccins, \u00e9valuer leur balance b\u00e9n\u00e9fice-risque dans les contextes locaux, produire des donn\u00e9es probantes utiles aux politiques de remboursement : tout cela demande des approches pharmaco\u00e9pid\u00e9miologiques encore insuffisamment int\u00e9gr\u00e9es dans plusieurs autorit\u00e9s africaines. Le renforcement des comp\u00e9tences et des collaborations entre autorit\u00e9s r\u00e9glementaires, universit\u00e9s et institutions de recherche est donc une priorit\u00e9.<\/p>\n<p>Les intervenants ont \u00e9galement beaucoup insist\u00e9 sur la compl\u00e9mentarit\u00e9 entre <strong>pharmacovigilance et pharmaco\u00e9pid\u00e9miologie<\/strong>. La pharmacovigilance peut d\u00e9tecter un signal. La pharmaco\u00e9pid\u00e9miologie permet ensuite de le quantifier, de le caract\u00e9riser et d\u2019identifier les populations \u00e0 risque. Ces r\u00e9sultats peuvent enfin \u00eatre r\u00e9int\u00e9gr\u00e9s dans l\u2019\u00e9valuation r\u00e9glementaire et d\u00e9boucher sur une action. Le cas canadien de l\u2019ondans\u00e9tron pendant la grossesse a montr\u00e9 concr\u00e8tement cette cha\u00eene qui va du signal \u00e0 la d\u00e9cision.<\/p>\n<div class=\"pe-chain\">\n<div class=\"pe-step\"><i>1<\/i><b>Pharmacovigilance<\/b><span>D\u00e9tecter un signal<\/span><\/div>\n<div class=\"pe-step\"><i>2<\/i><b>Pharmacoepidemiology<\/b><span>Quantifier, caract\u00e9riser, identifier les populations \u00e0 risque<\/span><\/div>\n<div class=\"pe-step\"><i>3<\/i><b>Regulatory Review<\/b><span>R\u00e9int\u00e9grer les r\u00e9sultats<\/span><\/div>\n<div class=\"pe-step last\"><i>4<\/i><b>D\u00e9cision<\/b><span>D\u00e9boucher sur une action<\/span><\/div>\n<\/div>\n<h2>Par o\u00f9 commencer ?<\/h2>\n<p>En apparence, deux strat\u00e9gies s\u2019opposaient dans la discussion : investir d\u2019abord dans de grandes infrastructures de donn\u00e9es longitudinales, ou d\u00e9montrer rapidement la valeur de la pharmaco\u00e9pid\u00e9miologie \u00e0 partir des donn\u00e9es d\u00e9j\u00e0 disponibles. Au fil des \u00e9changes, il est apparu que ces deux approches se compl\u00e8tent.<\/p>\n<p>Les transformations en cours, qu\u2019il s\u2019agisse de la digitalisation des soins, du d\u00e9veloppement des assurances maladie ou des syst\u00e8mes d\u2019information hospitaliers et pharmaceutiques, sont autant d\u2019occasions d\u2019int\u00e9grer d\u00e8s maintenant des identifiants uniques, des codifications standardis\u00e9es et des m\u00e9canismes de gouvernance adapt\u00e9s. En parall\u00e8le, des \u00e9tudes cibl\u00e9es peuvent \u00eatre men\u00e9es avec les donn\u00e9es disponibles pour d\u00e9montrer la valeur concr\u00e8te de la discipline, notamment en mati\u00e8re de s\u00e9curit\u00e9 des m\u00e9dicaments, de r\u00e9sultats cliniques ou de co\u00fbts \u00e9vit\u00e9s.<\/p>\n<p>Les \u00e9changes avec le public ont rappel\u00e9 que cette \u00e9volution devra aussi tenir compte des r\u00e9alit\u00e9s du terrain : une notification des effets ind\u00e9sirables plus simple, la prise en compte des conditions de stockage et de distribution des produits, un retour d\u2019information vers les professionnels qui collectent les donn\u00e9es et une meilleure information des patients.<\/p>\n<h2>En conclusion<\/h2>\n<div class=\"pe-concl\">\n<p>Le d\u00e9veloppement de la pharmaco\u00e9pid\u00e9miologie en Afrique n\u2019exige pas de construire d\u2019abord une infrastructure unique avant de pouvoir agir. Il passe par une progression men\u00e9e de front : <strong>mieux exploiter d\u00e8s aujourd\u2019hui les donn\u00e9es disponibles, d\u00e9montrer la valeur des \u00e9tudes pour la d\u00e9cision, renforcer les comp\u00e9tences et construire progressivement des syst\u00e8mes de donn\u00e9es plus fiables et interconnect\u00e9s<\/strong>.<\/p>\n<p>\u00c0 terme, l\u2019ambition est que la pharmaco\u00e9pid\u00e9miologie devienne plus qu\u2019une discipline acad\u00e9mique : une <strong>infrastructure permanente de d\u00e9cision<\/strong>, au service de la s\u00e9curit\u00e9, de l\u2019efficacit\u00e9, de l\u2019efficience et de l\u2019\u00e9quit\u00e9 des syst\u00e8mes de sant\u00e9 africains.<\/p>\n<\/div>\n<h2>Ressources du panel<\/h2>\n<div class=\"pe-replay\" id=\"replay\">\n<p class=\"pe-replay-k\">Replay<\/p>\n<p class=\"pe-replay-t\">Revoir l\u2019int\u00e9gralit\u00e9 du panel<\/p>\n<div class=\"pe-video\"><iframe src=\"https:\/\/www.youtube.com\/embed\/WwVTQq85_4s\" title=\"Replay du panel SeminalSeminars\u00ae : Pharmaco\u00e9pid\u00e9miologie en Afrique, des donn\u00e9es \u00e0 la d\u00e9cision\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<p><a class=\"pe-btn\" href=\"https:\/\/www.youtube.com\/watch?v=WwVTQq85_4s\" target=\"_blank\" rel=\"noopener\">Regarder sur YouTube<\/a><\/div>\n<p class=\"pe-pres-t\" id=\"presentations\">Pr\u00e9sentations des pan\u00e9listes<\/p>\n<p class=\"pe-pres-i\">Les supports pr\u00e9sent\u00e9s lors du panel, partag\u00e9s avec l\u2019accord de leurs auteurs.<\/p>\n<div class=\"pe-pres\">\n<div class=\"pe-card\">\n<p class=\"pe-name\">Dr Lassan\u00e9 Kabor\u00e9<\/p>\n<p class=\"pe-aff\">CEHPI \u00b7 Burkina Faso<\/p>\n<p class=\"pe-tt\">Pharmaco\u00e9pid\u00e9miologie en Afrique\u00a0: de l\u2019usage r\u00e9el \u00e0 la d\u00e9cision<\/p>\n<p><a class=\"pe-dl\" href=\"https:\/\/cehpi.com\/wp-content\/uploads\/2026\/10\/Presentation_KABORE.pdf\" target=\"_blank\" rel=\"noopener\">T\u00e9l\u00e9charger le PDF<\/a><\/div>\n<div class=\"pe-card\">\n<p class=\"pe-name\">Prof. Ars\u00e8ne Zongo<\/p>\n<p class=\"pe-aff\">Universit\u00e9 Laval \u00b7 Canada<\/p>\n<p class=\"pe-tt\">Construire une pharmaco\u00e9pid\u00e9miologie robuste et durable en Afrique<\/p>\n<p><a class=\"pe-dl\" href=\"https:\/\/cehpi.com\/wp-content\/uploads\/2026\/10\/Presentation_ZONGO.pdf\" target=\"_blank\" rel=\"noopener\">T\u00e9l\u00e9charger le PDF<\/a><\/div>\n<div class=\"pe-card\">\n<p class=\"pe-name\">Dr Lucresse C.A. Fassinou<\/p>\n<p class=\"pe-aff\">Experte ind\u00e9pendante \u00b7 B\u00e9nin<\/p>\n<p class=\"pe-tt\">Donn\u00e9es de vie r\u00e9elle en Afrique\u00a0: de la donn\u00e9e disponible \u00e0 la preuve utile<\/p>\n<p><a class=\"pe-dl\" href=\"https:\/\/cehpi.com\/wp-content\/uploads\/2026\/10\/Presentation_FASSINOU.pdf\" target=\"_blank\" rel=\"noopener\">T\u00e9l\u00e9charger le PDF<\/a><\/div>\n<div class=\"pe-card\">\n<p class=\"pe-name\">Myriam Salem<\/p>\n<p class=\"pe-aff\">Experte ind\u00e9pendante \u00b7 Canada<\/p>\n<p class=\"pe-tt\">Du signal \u00e0 la d\u00e9cision r\u00e9glementaire\u00a0: pharmacovigilance et pharmaco\u00e9pid\u00e9miologie<\/p>\n<p><a class=\"pe-dl\" href=\"https:\/\/cehpi.com\/wp-content\/uploads\/2026\/10\/Presentation_SALEM.pdf\" target=\"_blank\" rel=\"noopener\">T\u00e9l\u00e9charger le PDF<\/a><\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>D\u00e9fis, opportunit\u00e9s et perspectives pour les syst\u00e8mes de sant\u00e9 africains Panel en ligne du 9 octobre 2026 \u00b7 CEHPI \u00b7 \u25b6 Voir le replay \u00b7 Pr\u00e9sentations (PDF) Le 9 octobre [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"categories":[121,122],"tags":[],"class_list":["post-14255","post","type-post","status-publish","format-standard","hentry","category-formations","category-seminaires"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.3 - aioseo.com -->\n\t<meta name=\"description\" content=\"D\u00e9fis, opportunit\u00e9s et perspectives pour les syst\u00e8mes de sant\u00e9 africainsPanel en ligne du 9 octobre 2026 \u00b7 CEHPI \u00b7 \u25b6 Voir le replay \u00b7 Pr\u00e9sentations (PDF)Le 9 octobre 2026, CEHPI a organis\u00e9 la deuxi\u00e8me \u00e9dition de SeminalSeminars\u00ae. 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